Cincinnati, Ohio consumer recall attorney and defective drug lawyer reviewing Metformin injury lawsuits and diabetes drug complications for plaintiffs nationwide
In 2015 the American Diabetes Association (ADA) reported over 30 million Americans, or around nine percent of the population, had diabetes. Another 1.5 million diabetes patients are diagnosed each year.
Patients are typically moved onto various diabetes drugs and medications, including inculin, Metformin, Sulfonylureas, Meglitinides, Thiazolidinediones, DPP-4 inhibitors, GLP-1 receptor agonists, and SGLT-2 inhibitors. Metformin is used in medication under the brand names Glumetza, Riomet, Fortamet, Glucophage, and Janumet.
According to the Mayo Clinic, metformin is usually one of the first medications prescribed for type 2 diabetes, and is the most extensively used oral therapeutic agent for type 2 diabetes mellitus (T2DM).
The American Diabetes Association and other medical experts recommend it as the first line treatment for T2DM. However, the drug is not without risks. Patients have reported serious health issues and Metformin injury, including kidney disease, and liver damage.
A report published by Diabetes Care analyzed data from several studies and found individuals taking a metformin drug performing significantly worse on cognitive performance tests. Patients with type 2 diabetes performed poorly on cognitive impairment tests, with patient taking metformin performing even worse.
The researchers also found metformin was associated with a vitamin B12 deficiency, potentially linked to the impaired cognitive performance. Metformin has been called a wonder drug in treating type 2 diabetes, and has saved lives, though is not without health risks. The FDA is now investigating whether Metformin is contaminated with cancer-causing contaminants.
Joe Lyon is a highly-rated pharmaceutical injury attorney investigating diabetes drug amputations and Metformin injury and complications for injured plaintiffs.
The Lyon Firm works with industry experts to build the strongest case and engage large drug companies following drug defect injury.
Metformin Injury & Complications
Metformin continues to be heavily prescribed, in conjunction with other diabetes medications. Currently, over 150 million people worldwide are using metformin in some form. The most common side effects include gastrointestinal distress, nausea, diarrhea and upper abdominal discomfort. A larger concern is the potential for lactic acidosis, which can be serious.
Metformin may cause lactic acidosis when lactic acid production is high and lactic acid disposal is reduced, such as in cases of circulatory failure, sepsis, and anoxia or hypoxia.
What is Diabetes?
Diabetes is a disease described when blood sugar (glucose) levels are too high in an individual. Glucose is generally replenished with foods and beverages a person consumes. Most people consume sugars and their body responds by releasing insulin, a hormone that breaks sugars down into glucose. The glucose becomes a person’s basic energy source.
But patients with diabetes have trouble with this process. With type 1 diabetes, the body will not produce enough insulin, and in type 2 diabetes, the body may not use insulin properly. In both types, there is too much glucose in the blood, and leads to complications and the need for medications. Without diabetes drugs, patients risk heart attacks, strokes, kidney disease and other health risks.
Diabetes medications are designed to assist the body balance glucose levels, though some drugs, including Invokana, Onglyza and others may lead to more severe drug injury. There are a variety of diabetes medications that may keep blood sugar levels under control. Incretin mimetics, for example, are a drug that “mimics” incretin hormones, prompting the pancreas to release more insulin.
Another popular diabetes drug is Invokamet, which is a SGLT2 inhibitor combined with metformin. But Invokana and Invokamet may increase the risk of ketoacidosis, acute kidney injury, urinary tract infections, bone fractures, and leg and foot amputations.
Metformin Cancer Risk
Following reports of contamination of N-nitrosodimethylamine (NDMA) in metformin in other countries, the FDA is addressing the levels of NDMA in the nation’s metformin supply. This FDA action follows a recent statement regarding similar NDMA contamination in ranitidine and a recall of generic angiotensin II receptor blockers.
A Metformin recall has not been initiated at this point. As of now, the FDA suggests patients continue taking metformin to keep their diabetes symptoms under control. Metformin is the first-line drug used for high blood sugar levels in type 2 diabetes patients.
Levels of NDMA have been found in metformin supplies in other countries, according to the FDA. The acceptable daily intake limit for NDMA is the U.S. is set at 96 nanograms. Toxic substances like NDMA may increase the risk of cancer if people are exposed to unacceptable levels or have long-term exposure.
If you or a loved one has suffered a metformin or diabetes drug injury, and have questions about the legal remedies available to improve quality of life and medical care in Ohio, contact The Lyon Firm at (800) 513-2403. You will speak directly with Mr. Lyon, and he will help you answer these critical questions.