Drug Injury attorney and pharmaceutical defect lawyer reviews Ibuprofen Stevens Johnson Injury & Drug Use Associated with Adverse Drug Reactions and Rare Health Conditions


According to the World Health Organization (WHO) Website, the majority of Stevens-Johnson syndrome (SJS) cases are linked to drug exposures. Common over-the-counter medications like Motrin and Tylenol have added warnings to their labels regarding the use of their products, noting past cases of SJS. Ibuprofen, another common NSAID on the market, may also directly cause SJS, according to recent medical reports.

Stevens-Johnson is a severe blistering rash affecting both skin and mucous membranes. The reaction typically begins with burning and painful lesions on the face and torso and extends to the rest of the body. Patients have presented with fever, malaise, myalgia and ocular manifestations. SJS can be fatal, and death occurs in around 5 percent of known cases.

In about a 30-year period, Health Canada received 4 reports of SJS suspected of being associated with ibuprofen. The reports involved patients ages 13 to 34 years old. The ibuprofen daily dosages ranged from 200 mg to 1200 mg. The onset of reactions varied from the day of administration to approximately 15 days after starting ibuprofen use.

Ibuprofen has been available over-the-counter since 1989, and no warning label or health agency has mentioned a relation to SJS until recently. Cases of SJS are rare, although patients taking ibuprofen should discontinue use and seek medical attention if any rash or fever develop.

Joe Lyon is a highly-rated Cincinnati pharmaceutical injury attorney and Ohio product liability lawyer representing plaintiffs nationwide in a wide variety of civil litigation claims against pharmaceutical companies. 


What is Stevens Johnson Syndrome?

Stevens-Johnson syndrome is a rare condition, which is usually a reaction to a medication or an infection. It presents with flu-like symptoms, followed by a painful rash that spreads and blisters. The top layer of the affected skin dies, sheds and then heals.

SJS is a medical emergency that may require hospitalization. Treatment focuses on eliminating the underlying cause, controlling symptoms and minimizing complications. Recovery can take weeks to months, depending on the severity of the reaction.

ibuprofen stevens johnson


Common symptoms:

  • Fever
  • Widespread skin pain
  • A red or purple skin rash
  • Blisters on skin and the mucous membranes of the mouth, nose, eyes and genitals
  • Shedding of your skin within days after blisters form
  • Sore mouth and throat
  • Fatigue
  • Cough
  • Burning eyes

Ibuprofen Stevens Johnson Causes

Stevens-Johnson syndrome is a rare and unpredictable reaction, usually triggered by a medication or an infection. A reaction to medication may start while you’re using it or up to two weeks after you’ve stopped using it. Drugs that may cause Stevens-Johnson syndrome include:

  • Anti-gout medications—allopurinol
  • Seizure medications
  • Anticonvulsants and antipsychotics
  • Pain relievers, such as acetaminophen (Tylenol), ibuprofen (Advil, Motrin IB) and naproxen sodium (Aleve)
  • Antibiotics and anti-infection medications, such as penicillin

The FDA has issued SJS-related warnings on the following:

  • Advil Allergy Sinus Tablets
  • Advil Cold & Sinus Tablets
  • Advil Liqui-Gels
  • Advil Migraine Capsules
  • Tolectin 600 Tablets
  • Tolectin DS Capsules
  • Children’s Motrin Chewable Tablets (50 mg ibuprofen)
  • Motrin Junior Strength Chewable Tablets (100 mg ibuprofen)
  • Motrin Cold & Sinus

Drug Injury Lawsuits & Settlements

Following any drug-related injury, including cases of SJS and other unusual health conditions, injured plaintiffs should contact a medical professional and product liability attorney to determines the root cause of an ibuprofen Stevens Johnson injury and to work toward a medical and legal solution.

The Lyon Firm has experience engaging large drug corporations in defective drug cases and has obtained large injury settlements that have in turn helped victims pay for medical expenses and lost wages due to illness.

Joe Lyon works with pharmaceutical experts and is well-versed in a variety of areas in toxic tort and product liability litigation, and is prepared to represent injured plaintiffs in seeking the maximum benefit following preventable ibuprofen Stevens Johnson injuries.

Drug companies have a duty to properly test their products in trials before they release dangerous drugs to the public, even over-the-counter, where consumers risk their good health.

If you or a loved one has suffered an injury due to Ibuprofen use, and have questions about the legal remedies available to improve quality of life and medical care, contact The Lyon Firm at (800) 513-2403. You will speak directly with Mr. Lyon, a drug injury lawyer, and he will help you answer critical questions regarding ibuprofen Stevens Johnson injury.