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Cardiovascular Events

Ohio Catastrophic Injury and Product Liability Lawyer


Over the past ten years, several notable mass tort pharmaceutical claims have involved allegations that widely used medications cause cardiovascular events. Recent examples include the drugs Avandia, Vioxx, and Yaz (Yasmin). Currently, there are hundreds of lawsuits pending involving Testosterone Replacement Therapy. There are allegations that the medication causes the development of cardiovascular events at higher rates than the pharmaceutical companies had previously warned.

More and more medical literature is suggesting medications aimed to improve a quality of life may put healthy patients at risk of cardiac events. The American Heart Association has released statements that warn many prescription and over-the-counter drugs can cause or worsen heart failure.

Joe Lyon is a highly rated and experienced Cincinnati Personal Injury Lawyer who has  represented numerous individuals in serious cardiac incident cases in various types of law, ranging from Pharmaceutical Liability, Medical Malpractice, and even Catastrophic Injury.


Serious Cardiovascular Thrombotic Events

Cardiovascular events refer to any event that may cause damage to the heart. Some common events include the following:

  1. Deep vein thrombosis
  2. Heart attack
  3. Pulmonary embolus
  4. Stroke
  5. Myocardial infarction
  6. Aortic Dissection

 Injuries Caused by Cardiovascular Thrombotic Events

  1. Facial Palsy
  2. Heart Damage
  3. Arterial Damage
  4. Paralysis
  5. Wrongful Death

 Causes of Cardiovascular Events

Medical science has long identified contributing factors to cardiac events. Some are more natural, and other causes, such as damaging medications, have only recently been associated with heart issues. The most commonly known triggers are listed below:

  1. Medication
  2. Hypertension
  3. Diabetes
  4. Inherited genetic clotting traits
  5. Obesity
  6. Alcohol Abuse
  7. Smoking

 Medication Linked to Aortic Dissection


Fluoroquinolones have been linked to higher than average rates of Aortic Dissection and other cardiac events in a varied and growing body of medical literature. Studies,  by the American Medical Association and numerous medical journals, show a link between the use of fluoroquinolone antibiotics create a substantial risk for aortic aneurysms and aortic dissections. The 2015 studies identify an association between these drugs and potentially fatal cardiac injuries.

Popular fluoroquinolones include:

•    Avelox (moxifloxacin)
•    Cipro (ciprofloxacin)
•    Levaquin (levofloxacin)
•    Noroxin (norfloxacin)


 Testosterone Products Associated with Cardiac Events

Based on a review in 2014, the U.S. Food and Drug Administration (FDA) concluded that there is a possible increased cardiovascular risk associated with testosterone use. Based on the findings, the FDA also required the drug manufactures to supplement the warning labels to include additional testosterone therapy side effects. Therapy with testosterone products has been suspected of contributing to a high risk of heart attacks, pulmonary embolus, deep vein thrombosis, and strokes.
Specific products named include the following drugs:
•    Androgel
•    Fortesta
•    Depo Testosterone
•    Axiron
•    Androderm

Proving the Cardiovascular Event was Caused by the Medication 


The question of causation in toxic tort cases is always complex and requires expert testimony that is based in reliable data and facts, reliable scientific methodology, and application of the facts to the methodology.  Credible medical literature and foundational case specific facts are paramount.

Under Ohio law and the law of many states, it is not necessary that the Plaintiff prove that the medication was the sole cause of the injury. In toxic tort cases, Ohio Courts have applied the ” substantial contributing factor” test on causation. In layman’s terms, risk factors do not preclude a finding of liability. As long as the medication played a substantial role in causing the cardiovascular event, in combination with the risk factors, the law supports a finding of liability against the drug company for failing to warn about the side effect.

Legal Representation


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Joe Lyon successfully represented plaintiffs in Vioxx, Yaz, and Avandia.  The Lyon Firm is currently representing Plaintiffs in Testosterone Replacement Therapy and making similar arguments on the mechanism of injury between the medication and association with cardiovascular events. For questions related to cardiovascular events and medication, contact The Lyon Firm.

If you need help understanding whether a pharmaceutical product was a contributing factor in causing a cardiovascular event, or whether a delay in medical care allowed such an event to occur, call The Lyon Firm at 800.513.2403 to speak with Mr. Lyon directly.

While we cannot take every case, we strive to provide more information to each client than what they had when they called.  

After two hip replacement surgeries, I was informed that one of the prosthesis was the DuPuy Joint and the other was very similar but manufactured by a different company. After several attempts to contact the manufacturer directly to discuss the claim, I was met with bureaucratic red tape that appeared to be insurmountable. I then turned to Joe Lyon of the Lyon Law Firm who immediately cut through the pro I highly recommend Joe if you are faced with the need for this type of litigation.Tim Ross
I met Joe during what was easily one of the worst times of my life. My husband had been in a serious accident and was a quadriplegic following that accident and remained in one medical facility after another until his death nearly four years later. We had contacted an area attorney who told us we absolutely did not have a case. Then we called a Cleveland firm that took the case and brought in Joe. Joe did so much of the work and became just like family to us. I would highly recommend Joe to anyone and be willing to guarantee that he will do anything and everything possible to get satisfactory results. He is extremely dedicated to his clients and very hard working. Mike and I came to think of him like a son, I still do; if it wasn’t for him I don’t believe our case would have been settled the way it was and may have ended up in a courtroom where the results can go any way.Donna Urchak